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  • 73 Why has there been so little progress on Alzheimer's disease? (freakonomics.com)
    by chiefalchemist 2 hours ago | 32 comments
  • 175 USB Cheat Sheet (2022) (fabiensanglard.net)
    by gwerbret 5 hours ago | 46 comments
  • 278 The Free Universal Construction Kit (fffff.at)
    by robinhouston 4 days ago | 54 comments
  • 107 OpenAI Privacy Filter (openai.com)
    by tanelpoder 3 days ago | 16 comments
  • 46 Flickr: The first and last great photo platform (petapixel.com)
    by Nrbelex 3 days ago | 12 comments
  • 527 1-Bit Hokusai's "The Great Wave" (2023) (hypertalking.com)
    by stephen-hill 4 days ago | 87 comments
  • 190 Using coding assistance tools to revive projects you never were going to finish (blog.matthewbrunelle.com)
    by speckx 10 hours ago | 113 comments
  • 69 America's Geothermal Breakthrough (oilprice.com)
    by sleepyguy 7 hours ago | 83 comments
  • 86 The Joy of Folding Bikes (blog.korny.info)
    by pavel_lishin 3 days ago | 54 comments
  • 6 An amateur just solved a 60-year-old math problem–by asking AI (scientificamerican.com)
    by pr337h4m 9 hours ago | discuss
  • 37 Math Is Hard – OpenBSD Stories (miod.online.fr)
    by signa11 2 days ago | discuss
  • 41 Her Life Savings Mysteriously Disappeared After a Systems Glitch (nytimes.com)
    by danso 3 hours ago | 31 comments
  • 19 Optimizing Datalog for the GPU (dl.acm.org)
    by tosh 3 days ago | discuss
  • 548 New 10 GbE USB adapters are cooler, smaller, cheaper (jeffgeerling.com)
    by calcifer 20 hours ago | 322 comments
  • 99 Simulacrum of Knowledge Work (blog.happyfellow.dev)
    by thehappyfellow 9 hours ago | 35 comments
  • 65 How Hard Is It to Open a File? (blog.sebastianwick.net)
    by ffin 2 days ago | 8 comments
  • 74 Mine, an IDE for Coalton and Common Lisp (coalton-lang.github.io)
    by varjag 9 hours ago | 24 comments
  • 8 The Long Reply (ironicsans.ghost.io)
    by NaOH 2 days ago | discuss
  • 164 What async promised and what it delivered (causality.blog)
    by zdw 4 days ago | 185 comments
  • 108 Desmond Morris has died (bbc.com)
    by martey 5 days ago | 19 comments
  • 162 Martin Galway's music source files from 1980's Commodore 64 games (github.com)
    by ingve 16 hours ago | 23 comments
  • 45 Show HN: Kloak, A secret manager that keeps K8s workload away from secrets (getkloak.io)
    by neo2006 7 hours ago | 35 comments
  • 148 Discret 11, the French TV encryption of the 80s (fabiensanglard.net)
    by adunk 15 hours ago | 27 comments
  • 132 GPT‑5.5 Bio Bug Bounty (openai.com)
    by Murfalo 12 hours ago | 98 comments
  • 62 Lute: A Standalone Runtime for Luau (lute.luau.org)
    by vrn-sn 3 days ago | 11 comments
  • 52 Colorado Adds Open-Source Exemption to Age-Verification Bill (fosstodon.org)
    by terminalbraid 4 hours ago | 6 comments
  • 107 Can you stop beans from making you gassy? (seriouseats.com)
    by jstrieb 6 hours ago | 83 comments
  • 37 Agents Aren't Coworkers, Embed Them in Your Software (feldera.com)
    by gz09 3 hours ago | 14 comments
  • 51 Which one is more important: more parameters or more computation? (2021) (parl.ai)
    by jxmorris12 a day ago | 9 comments
  • 114 A web-based RDP client built with Go WebAssembly and grdp (github.com)
    by mariuz 15 hours ago | 44 comments